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1008 Pathology

A 42-year-old woman gives birth to a neonate with multiple congenital abnormalities. Physical findings included a flat facial profile, slanted eyes, epicanthal folds, Brushfield spots, short nose, short neck, dysplastic ears, clinodactyly, a large protruding tongue, and a pronounced heart murmur. As an adult, the brain of the patient will show histopathologic changes that are seen in patients with which of the following neurologic diseases?

AAlzheimer disease
BHuntington disease
CKrabbe disease
DMultiple sclerosis
Pathology
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