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9961 Pathology

A 10-year-old girl complains of persistent redness of the skin over her knuckles and around the nail beds. She describes easy fatigability and can rise only with difficulty from a squatting position. Physical examination reveals erythema over the knuckles and a heliotropic rash. A muscle biopsy shows infiltrates of B and T lymphocytes around blood vessels and in connective tissue of the perimysium. Elevated serum levels of which of the following would be expected in this patient?

AAlkaline phosphatase
BAlpha-fetoprotein
CCarcinoembryonic antigen
DCreatine kinase
Pathology
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