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5609 Microbiology

A 27-year-old male patient (blood group O) arrives at the emergency room with a massive intestinal bleed (hematochezia) Within hours he has lost half of his blood volume, and you decide to transfuse. Due to human error, you transfuse blood group AB into him and within minutes he develops a fever, chills, dyspnea, and a dramatic drop in blood pressure. This reaction is most likely due to which of the following?

AA cell-mediated response against AB antigens
BIgG production by the recipient in response to AB antigens
CPreformed anti-A and anti-B antibodies in the recipient
DPreformed anti-A and anti-B antibodies of the blood donor
Microbiology
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