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9343 Microbiology

A 1-week-old neonate presents to the pediatric emergency room with fever, irritability, poor feeding, and a bulging anterior fontanelle. Lumbar puncture is performed, and the cerebrospinal fluid (CSF) grows group B Streptococcus. Which of the following is the most likely pathogenic mechanism?

AComplement C5a, a potent chemoattractant, activates polymorphonuclear neutrophils (PMNs)
BIn the absence of a specific antibody, opsonization, phagocyte recognition, and killing do not proceed normally
CThe alternative complement pathway is activated
DThe streptococci are resistant to penicillin
Microbiology
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9344 Microbiology

A 63 year old male with a 75 pack year history of smoking and marked chronic obstructive pulmonary disease (COPD) develops fevers and a persistent cough frequently tinged with blood. Chest x-ray reveals a complex cavitary lesion in the right upper lobe. Bronchoscopic examination identifies a large lung abscess from which pure Fusobacterium nucleatum is cultured. What is the most likely source of the Fusobacterium?

ABlood
BInfected aerosols
COral cavity
DStomach
Microbiology
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