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8562 Medicine

True about polymorphism is:

ASingle locus --> multiple normal alleles
BSingle locus --> multiple abnormal alleles
CSingle phenotype:Single locus -+ multiple normal alleles
DSingle phenotype: Single locus --> multiple abnormal alleles
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8564 Medicine

A-12-year old boy presents to the Outpatient department with a history of progressively increasing difficulty in walking and frequent falls. Physical Examination reveals an ataxic gait and nystagmus. All deep tendon reflexes were observed to be absent while the plantar response was ‘Extensor’. What is the most likely diagnosis?

AFriedreich's Ataxia
BSubacute Combined Degeneration of Cord (SACD)
CBecker's Muscular Dystrophy
DTabes Dorsalis
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8568 Medicine

A 50-year-old man presents to the clinic complaining of fatigue and painful swelling of both hands. He also describes being very “stiff’ in the morning and requires much longer time to get ready for work. On physical examination, there is erythema, swelling, and tenderness on palpation of the proximal interphalangeal joints and MCP joints. The pattern of joint swelling is symmetric. Plain x-rays of the hand are ordered. Which of the following x-ray findings is characteristic of this condition?

Aloss of articular cartilage and bone erosion
Bnormal
Costeolytic changes
Dosteosclerotic changes
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