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8106 Medicine

Varicella-zoster virus (VZV) is the cause of chickenpox and herpes zoster. Which of the following statements are true or false? a) Humans are the only known reservoir for VZV b) Secondary and teiary cases within families are associated with a relatively small number of vesicles c) The most common infectious complication of varicella is secondary bacterial superinfection of the skin, which is usually caused by Streptococcus pyogenes or Staphylococcus aureus d) Varicella pneumonia, the most serious complication following chickenpox e) Perinatal varicella is associated with a high moality rate

Aa,c, e-True b,d-False
Ba,c,d,e-True b-False
Cb,c,d,e-True a-False
Da,b,c,d,e-True None -False
Medicine
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8107 Medicine

A four year old boy was admitted with a history of abdominal pain and fever for two months maculo popular rash for ten days, and dry cough, dyspnea and wheezing for three days. One examination liver and spleen were enlarged 4 cm and 3 cm respectively below the costal margins. His hemoglobin was 10.0 g/dl, platelet count 37x 109/L and total leukocyte count 70 x 109L, which included 80% eosinophils Bone marrow examination revealed a cellular marrow comprising of 45% blasts and 34% Eosinophils and eosinophilic precursors. The blasts stained negative for myeloperoxidase and non-specific esterase and were positive for CD19, CD10, CD22 and CD20. Which of the following is the most likely diagnosis?

ABiphenotypic acute leukemia (lymphoid and eosinophil lineage
BAcute eosinophilic leukemia
CAcute lymphoblastic leukemia with hypereosinophilic syndrome
DAcute myeloid leukemia with eosinophilia
Medicine
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