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5843 Medicine

A 35 year old female presents to OPD with complaints of fatigue and weakness. She has had decreased appetite, weight loss, and severe light-headedness upon standing. Vital signs show a hea rate of 88 bpm, respiration rate of 18 breaths per minute, and temperature of 37.2deg C. The exam is remarkable for pigmentation of the oral mucosa, proximal muscle weakness of the lower extremities, and hyperpigmentation of the palmar creases, knuckles and knees. What is the most likely diagnosis?

AAdrenal insufficiency
BDepression
CAnorexia with surreptitious diuretic use
DHypothyroidism
Medicine
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5844 Medicine

A 34-year-old woman presents to the clinic for evaluation of new symptoms of a red rash over her cheeks, frequent oral ulcers, and pain and swelling in both wrists, as well as in several small joints in her hands. Medical evaluation confirms the above clinical symptoms and laboratory investigations reveal a positive ANA, and 3+ proteinuria. Which of the following organ involvement will cause the most symptoms during the course of this disease?

Arenal pathology
Bcardiopulmonary pathology
Cmusculoskeletal pathology
Dthrombotic events
Medicine
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