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3730 Medicine

A 23-year-old woman has had several episodes of severe wheezing over the past 3 years. She is a nonsmoker and feels well in between episodes. She has no personal or family history of atopy. The wheezing episodes are most likely to occur in spring. Which of the following is the most likely mechanism of wheezing in this woman?

Aelevated IgE levels
Bmast cell instability
Cnonspecific hyperirritability of the tracheobronchial tree
Ddisordered immediate hypersensitivity
Medicine
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