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3422 Medicine

A 12 months old girl of Punjabi parents developed a pallor since 3 months of age. One unit of blood transfusion was done at 5 months of age. Now presents with pallor, on examination hepatosplenomegaly. Hematoglobin was 3.8 gin/d1, MCV=68, MCH=19. Peripheral smear showed schistocytes. one marrow examination show erythroid hyperplasia. Diagnosis is –

ASickle cell anemia
BAlpha-thalassemia
CBeta-thalassemia (major)
DGlucose-6-phosphate dehydrogenase
Medicine
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