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2601 Medicine

All are true about cold agglutinin disease, EXCEPT:

AHemolysis is more prominent the more the body is exposed to the cold
BThe antibody is usually IgM with an anti-I specificity
CBlood transfusion is not very effective because donor red cells are I-positive and will be rapidly removed
DRituximab is not effective as a therapeutic measure as it can not control hemolysis effectively
Medicine
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