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1999 Medicine

A 26-year-old woman comes to the emergency complaining of 2 day of worsening right leg pain and swelling. She drove in a car 8 hours back from a hiking trip 2 days ago and then noticed some pain in the leg. At first she thought it was due to exeion, but it has worsened over the day. Her past medical history is related to difficulty getting pregnant, with two prior spontaneous aboions. Her physical examination is notable for normal vital signs, hea, and lung examination. Her right leg is swollen from the mid-thigh down and is tender. Doppler studies demonstrate a large deep venous thrombosis in the femoral and ileac veins extending into the pelvis. Laboratory studies show normal electrolytes, normal WBC and platelet counts, normal PT, and an aPTT 3x normal. Her pregnancy test is negative. Low-molecular-weight heparin therapy is initiated in the emergency depament. Subsequent therapy should include which of the following?

ARituximab 375 mg/m2 per week for 4 weeks
BWarfarin with international normalized ratio (INR) goal of 2.0-3.0 for 3 months
CWarfarin with INR goal of 2.0-3.0 for 12 months
DWarfarin with INR goal of 2.5-3.5 for life
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2004 Medicine

An 18-year-old woman is referred to your clinic after branch retinal aery occlusions occurred in each eye several months apa. Examination reveals moderate hearing loss in the right ear, in addition to visual field loss in each eye. A brain MRI reveals multiple small coical strokes in the frontal lobes and the left parietal lobe. Which of the following diagnosis fits best with this clinical presentation?

AMultiple sclerosis
BSusac syndrome
CAcute disseminated encephalomyelitis
DConversion reaction
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2006 Medicine

A six year old boy presents with echymoses and petichiae all over the body 2 weeks after an upper respiratory tract infection Abdominal examination is unremarkable with no hepatosplenomegaly All of the following statements about the affecting condition are true Except:

ABleeding into the joints is a common manifestation
BBone marrow will show increased megakaryocytes
CPlatelet count is decreased
DCondition resolves spontaneously in 80% of patients in 2 to 6 weeks
Medicine
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