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17170 Medicine

A 21 year old student is found to have hyperthyroidism. She is counselled on treatment options including radioactive iodine and antithyroid medications. Carbimazole acts on which part of the thyroid hormone synthesis pathway?

ACleavage of thyroglobulin by proteolysis
BCoupling of monoiodotyrosine (MIT) and diiodotyrosine (DIT) forming triiodothyronine CTsl and thyroxine (T4)
CDehalogenation of iodinated tyrosine to recycle iodide
DOrganification of iodide by thyroid peroxidase incorporating tyrosine forming MIT and DIT
Medicine
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