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16483 Medicine

A 30 years old male patient presents with complaints of weakness in right upper and both lower limbs of last 4 months. He developed digital infarcts involving 2nd and 3rd fingers on right side and 5`h fingeron left side. On examination, BP was 160/140 mm Hg, all peripheral pulses were palpable and there was asymmetrical neuropathy. Investigations showed a Hb 12 gm, TLC-12000 Cu mm, Platelets 4,30,000, ESR-49 mm. Urine examination showed proteinuria and RBC – 10-15/hpf with no casts. Which of the following is the most likely diagnosis?

APolyaeritis nodosa
BSystemic lupus erythematosus
CWegener's granulomatosis
DMicroscopic polyangitis
Medicine
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16484 Medicine

A 63-year-old man presents with weakness and hemoptysis, but no fever, cough, or sputum. He has a 60-pack-per-year history of smoking. The chest x-ray (CXR) reveals a lung mass with mediastinal widening. On examination, there is a blue purple discoloration of the upper eyelids and erythema on his knuckles. He has proximal muscle weakness rated 4+/5, normal reflexes, and sensation. Which of the following is the most likely diagnosis for his muscle weakness?

ASLE
Bscleroderma
Cdermatomyositis (DM)
Dpolyarteritis
Medicine
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