All Subjects Medicine Surgery Pathology Anatomy Pharmacology Social & Preventive Medicine Microbiology Gynaecology & Obstetrics Dental Physiology Biochemistry Pediatrics
Showing 18289 questions
Sort:
16120 Medicine

A 26-year-old healthy man comes to your clinic for an annual wellness examination. He does not take any medications. He smokes half pack of cigarettes daily. He tells you that his father died of colon cancer at the age of 45. He also has a 25-year-old cousin who recently had colonoscopy for rectal bleeding was found to have multiple polyps and is scheduled for total colectomy. Your patient wants to know if he can inherit colon cancer and if there is a way to find out if he is at risk. You talk to him about how some cancers can be caused by genetic mutations. For what genetic mutation is this patient at highest risk?

AMEN1
BRET
CAPC
DMSH
Medicine
View Explanation →
16122 Medicine

A 32 year old female presented with anxiety, palpitations, and diarrhea. Lab studies show elevated T4, TSH levels are low & increased long acting thyroid stimulating antibody titres. A diagnosis of Graves disease is made. But then the patient came to emergency with sudden onset of acute chest pain. CT angiography which is useful in making the diagnosis of pulmonary embolism, can be potentially dangerous in this patient because:

AIodinated contrast exposure in patients with Graves disease may exacerbate hypehyroidism.
BPulmonary embolism is exceedingly rare in Graves disease.
CRadiation exposure in patients with hypehyroidism is associated with increased risk of subsequent malignancy.
DTachycardia with Graves disease limits the image quality of CT angiography and will not allow accurate assessment of pulmonary embolism.
Medicine
View Explanation →