All Subjects Medicine Surgery Pathology Anatomy Pharmacology Social & Preventive Medicine Microbiology Gynaecology & Obstetrics Dental Physiology Biochemistry Pediatrics
Showing 18289 questions
Sort:
15250 Medicine

A family suffering a hereditary form of severe emphysema, with some family members also showing hepatic disease. Liver biopsy in one of the family members demonstrates increased reactivity with antibodies directed against a-1-antitrypsin. Serum levels of the enzyme are low, leading to increased activity of a number of serine proteases. Increased activity of which of the following serine proteases has been most closely tied to the emphysema that develops in these patients?

AChymotrypsin
BElastase
CPlasmin
DThrombin
Medicine
View Explanation →
15255 Medicine

A 78 year old man who lives alone and prepares his own food is found to have ecchymotic patches over posterior aspect of his lower extremities. He has haemorrhagic areas around hair follicles, hair are fragmented and splinter haemorrhages are present in nail beds and several hematomas are present in the muscles of arms and legs. PT and CT are normal. This clinical syndrome is most likely due to

AVitamin K deficiency
BVitamin C deficiency
CPyridoxine deficiency
DVitamin A deficiency
Medicine
View Explanation →