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14267 Medicine

A 70 year old male patient dies with severe dementia. Autopsy demonstrates marked atrophy of the frontal and temporal lobes, with relative sparing of the rest of the brain. Which of the following microscopic features would be most useful in establishing the diagnosis?

AEnlarged presynaptic axon terminals surrounding a central core of extracellular amyloid-like substance
BIntracytoplasmic spherules composed of paired helical filaments
CIntracytoplasmic spherules that stain brightly eosinophilic
DIntranuclear and intracytoplasmic inclusion bodies in enlarged cells
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14270 Medicine

An 80-year-old person has started forgetting the names of familiar persons and places. There has been confabulation. He tends to forget whether he has had his meals. Clinical and neurological examination reveals no abnormality.CT scan of the brain showed symmetrical enlargement of lateral ventricles and wider sulci. The most likely diagnosis is-

AConfusional state
BAlzheimer's disease
CAlcholol dementia
DChronic cerebrovascular insufficiency
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14272 Medicine

A 70 year old man is having nasal regurgitation of fluids and hoarseness of voice. On sensory examination numbness and loss of sensation over left half of face with impaired pain and temperature and contralateral pa of the body is noted. Motor examination shows left arm weakness and cranial nerve examination shows diminished gag reflex. Which of the following vessel thrombosis leads to this condition?

APosterior inferior cerebellar aery
BPosterior cerebral aery
CMiddle cerebral aery
DAnterior inferior cerebral aery
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