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9109 Medicine

A nine month old boy of Sindhi parents presented to you with complaints of pregressive lethargy, irritability & pallor since 6 months of age. Examination revealed severe pallor. Investigation showed Hb-3.8 mg%; MCV-58 fl; MCH-19.4 pg/ cell. Blood film shows osmotic fragility is normal (target cells and normoblasts). X-ray skull shows expansion of erythroid marrow. Which of the following is the most likely diagnosis –

AIron deficiency anemia
BAcute lymphoblastic anemia
CHemoglobin D disease
DHereditary spherocytosis
Medicine
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