Mcq Subject: Biochemistry

Unwinding Enzyme in DNA synthesis:

A. Helicase

B. Primase

C. DNA Polymerase

D. Transcriptase

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The major vitamin deficiency in Wernicke’s encephalopathy is :

A. B1

B. B2

C. B6

D. B12

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All are true about ketone bodies except

A. Acetoacetate is primary ketone body

B. Synthesized in mitochondria

C. Synthesized in liver

D. HMG CoA reductase is the rate-limiting enzyme

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To be defined as a ganglioside,a lipid substance isolated from nervous tissue must contain

A. NANA,hexose,fatty acid,glycerol

B. NANA,hexose,fatty acid,phosphorycholine

C. NANA,sphingosine,ethanolamine

D. NANA,hexose,sphingosine,long chain fatty acid,

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Excess of avidin causes deficiency of:

A. Folate

B. Choline

C. Vitamin B12

D. Biotin

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Insulin causes lipogenesis by all except:

A. Increasing acetyl-CoA carboxylase activity

B. Increases the transpo of glucose into the cells

C. Inhibits pyruvate dehydrogenase

D. Decreases intracellular cAMP level

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A four-year-old child is diagnosed with Duchenne muscular dystrophy, an X-linked recessive disorder. Genetic anylysis shows that the patient&;s gene for the muscle protein dystrophin contains a mutation in its promoter region. What would be the most likely effect of this mutation?

A. Tailing of dystrophin mRNA will be defective

B. Capping of dystropin mRNA will be defective

C. Termination of dystrophin transcription will be deficient.

D. Initiation of dystrophin transcription will be deficient

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Menke’s Kinky hair syndrome is due to defect in

A. Ca transporter

B. Cu transporter

C. Zn transporter

D. Se transporter

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Which of the following is the source of energy for a cardiac muscle at normal conditions?

A. Fatty acids

B. Ketone bodies

C. Glucose

D. Any of the above

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Which of the following is not a pyrimidine base?

A. Cytosine

B. Uracil

C. Guanine

D. Thymine

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