Mcq Subject: Biochemistry

Fat provides ____________ of body’s calories

A. 40%

B. 30%

C. 50%

D. 75%

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All of the following are true about Cholesterol Ester Transfer Protein(CETP) , EXCEPT:

A. Associated with HDL

B. Facilitates the transfer of cholesterol ester from HDL to LDL

C. Facilitates the transfer of triacylglycerol from LDL to HDL

D. Facilitates the transfer of triacylglycerol from HDL to LDL

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Which of the following is physiological uncoupler-

A. Thermogonin

B. 2, 4nitrophenol

C. 2, 4Dinitrophenol

D. Oligomycin

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A highly specific inhibitor that targets the phosphorylation activity of TFIIH is added to an in vitro transcription reaction. Which one of the following steps is most likely to be affected?

A. Binding of RNA polymerase to promoter sequence

B. Promoter clearance

C. Recruitment of TFIID

D. Open promoter complex formation

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Which of the following liver enzymes is predominantly mitochondrial?

A. SGOT (AST)

B. SGPT (ALT)

C. GGT

D. 5' Nucleotidase

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A 30 year old male patient was on Isoniazid therapy for Tuberculosis.He developed rashes on exposed pas of body.He has disoriented memory. Family members gives history of diarrhea also.What is the diagnosis?

A. Isoniazid neuropathy

B. Tuberculosis skin lesions

C. Niacin deficiency

D. Some other drugs has caused this

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Vitamin D from the skin or diet is metabolized primarily in the liver to 25-hydroxyvitamine D3. What is the rate limiting enzyme in Vitamin D synthesis?

A. 25 cholecalciferol

B. 1, 25-dihydroxycholecalciferol

C. 24, 25- dihydroxycholecalciferol

D. 7-dehydrocholesterol

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True about Type 1 diabetes mellitus

A. Decreased hepatic Glucose output

B. Increase glucose uptake

C. Increased lipolysis

D. Decreased protein catabolism

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Gamma Carboxylation of what requires vitamin K

A. Glutamine

B. Glutamic Acid

C. Glycine

D. Aspaate

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Frame shift mutation DOESN’T occur in multiples of:

A. 2

B. 3

C. 4

D. 5

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