Mcq Subject: Biochemistry

What is the function of DNA ligase ?

A. Unwinding (denaturation) of dsDNA to provide an ssDNA template

B. Seals the single strand nick between the nascent chain and Okazaki fragments on lagging strand

C. Initiation of DNA synthesis and elongation

D. Initiates synthesis of RNA primers

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Triglycerides are maximum in

A. Chylomicrons

B. VLDL

C. LDL

D. HDL

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Fluroacetate inhibits –

A. Citrate synthetase

B. Aconitase

C. Succinate dehydrogenase

D. Alphaketoglutarate dehydrogenase

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Farber&;s disease is due to the deficiency of

A. Ceraminidase

B. Sphingomyelinase

C. Glucocerebrosisase

D. Neuraminidase

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Enzyme Transketolase requires ?

A. FAD

B. TPP

C. PLP

D. FMN

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True-regarding DNA-replication:

A. Semi conservative

B. Sister Chromatids are formed.

C. Follow base pair rule

D. All of the above

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Concentration of which is inversely related to the risk of coronary hea disease

A. VLDL

B. LDL

C. HDL

D. None

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Which of the following is a suicidal enzyme

A. Cyclooxygenase

B. Lipooxygenase

C. 5-nucleotidase

D. Thrombaxane synthase

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Not a dietary source of vit. B12-

A. Fish

B. Meat

C. Soya bean

D. Liver

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Patients with diabetes frequently report changing visual acuities when their glucose levels are chronically high. Which of the following could explain the fluctuating acuity with high blood glucose levels?

A. Increased sorbitol in the lens

B. Decreased fructose in the lens

C. Increased oxidative phosphorylation in the lens

D. Macular degeneration

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