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6729 Biochemistry

An individual who has been treated for type 2 diabetes for the past 24 years had, as part of his annual physical, a 24-hour urine collection. Reduced levels of creatinine were found, which is most likely because of which one of the following?

AA decreased dietary intake of creatine
BA higher-than-normal muscle mass resulting from weightlifting
CA genetic defect in the enzyme that converts creatine phosphate to creatinine
DKidney failure (Correct Answer)