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6629 Biochemistry

Malonate is a competitive inhibitor of succinate dehydrogenase, a key enzyme in the Krebs tricarboxylic acid cycle. The presence of malonate will affect the kinetic parameters of succinate dehydrogenase in which one of the following ways?

AIncreases the apparent Km but does not affect Vmax. (Correct Answer)
BDecreases the apparent Km but does not affect Vmax.
CDecreases Vmax but does not affect the apparent Km
DIncreases Vmax but does not affect the apparent Km.