Mcq Subject: Biochemistry

Child presents with hypotonia and seizures. It was confirmed to be zellweger syndrome. Which of the following accumulates in brain?

A. Glucose

B. Lactic acid

C. Long chain fatty acid

D. Triglycerides

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Which of the following is not required for protein synthesis of eukaryotes:

A. RNA polymerase

B. Ribosomes

C. Peptidyl transferase

D. Amino acyl tRNA synthetase

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On laboratory investigations in a patient, LDL was highly elevated but the level of LDL receptors was normal. Which of the following is most probable cause?

A. Phosphorylation of LDL receptors

B. Lipoprotein lipase deficiency

C. Apo B-100 mutation

D. Cholesterol Acyl Co-A transferase deficiency

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A patient has normal blood glucose level as estimated by glucose-oxidase peroxidase method, shows positive Benedicts test in urine. Which of the following is the most likely cause?

A. Fructosemia

B. Denaturation of glucose

C. Galactosemia

D. False positive

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Which acid is formed in the citric acid cycle?

A. Oxaloacetic acid

B. Glutamic acid

C. Nitric acid

D. None of the above

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RNAi causes the following in a gene:

A. Knock in

B. Knock out

C. Knock down

D. Knock up

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The conversion of glucose-6-P to fructose-6-P is an example of which of the following reactions:

A. Phosphate transfer

B. Isomerisation

C. Dehydration

D. Aldol cleavage

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All of the following should be avoided by a patient with lactose intolerance, EXCEPT:

A. Condensed milk

B. Ice-cream

C. Skimmed milk

D. Yoghu

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In uncontrolled diabetes mellitus, elevated triglyceride and VLDL levels are seen due to:

A. Increased activity of lipoprotein lipase and decreased activity of hormone sensitive lipase

B. Increased activity of hormone sensitive lipase and decreased activity of lipoprotein lipase

C. Increase in peripheral LDL receptors

D. Increased activity of hepatic lipase

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Lipids are ………………group of compounds:

A. Heterogenous

B. Homogenous

C. None of the above

D. Any of the above

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