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53 Biochemistry

Glycogen synthesis and breakdown takes place in the same cell, having enzymes necessary for both the pathways. Why the glucose-6-phosphate, freshly synthesized during glycogenesis in cytoplasm of hepatocytes, is not immediately degraded by the enzyme glucose!6-phosphatase?

AThe thermodynamics does not or such a reaction to occur
BGlucose-6-phosphatase is present in the endoplasmic reticulum and cannot act on glycogen formed in the cytoplasm (Correct Answer)
CGlycogenesis and glycogenolysis are tightly regulated such that enzymes of only one of those is present at a time.
DSteric hindrance due to albumin