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4967 Biochemistry

The current therapeutic strategy for patients who have been infected with HIV is a multidrug regimen known as highly active antiretroviral therapy (HAA). One type of drug used in this therapy is a nucleoside/ nucleotide analog, such as didanosine. Which of the following best describes the mechanism of action of these drugs

AThey prematurely terminate the DNA synthesized by reverse transcriptase.
BThey prevent the hydrolysis of the viral polyprotein.
CThey directly bind to and inhibit reverse transcriptase.
DThey inhibit the synthesis of viral proteins.
Biochemistry
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