Mcq Subject: Biochemistry

Which of the following is not used in polymerase chain reaction?

A. DNA Polymerase

B. Taq polymerase

C. Dideoxyribonucleotides

D. DNA template

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All are true about CRISPR cas 9 Except

A. gRNA ensures that the Cas9 enzyme cuts at the right point in the genome

B. NHEJ repair & HDR pathway

C. C9 enzyme is used in CRISPR gene editing

D. All of these

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Which of the following does not or permissive euchromatin due to changes occurring at cytosine residues at CpG islands in DNA?

A. Methylation

B. Alkylation

C. Phosphorylation

D. Sumoylation

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One of the following is not an amino acid:

A. Glycine

B. Hydroxy proline

C. Glutamic acid

D. Choline

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The most important career of cholesterol in plasma is:

A. VLDL

B. LDL

C. HDL

D. Chylomicrons

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Thiamine deficiency is assessed by:

A. Erythrocyte transketolase activity

B. RBS Glutathione reductase

C. RBC thiamine levels

D. Serum thiamine level

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Which of the following conversions does not require Biotin as a cofactor?

A. Gamma carboxylation of glutamate

B. Acetyl Co-A to Malonyl Co-A

C. Propionyl Co-A to methyl malonyl Co-A

D. Pyruvate to oxaloacetate

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All of the following processes take place in mitochondria except:

A. Beta-oxidation of fatty acids

B. DNA synthesis

C. Fatty acid synthesis

D. Protein synthesis

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A male child presented with coarse facies, protuberant abdomen , frontal head enlargement, thickening of cardiac valve, hepatosplenomegaly, hearing impairement. What is the most probable diagnosis?

A. Hurler's disease

B. Hunter's disease

C. Fragile X syndrome

D. Tay Sach's disease

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Mother to children’s transmission is a key feature of which pattern of inheritance?

A. Codominance

B. Autosomal dominant inheritance

C. Recessive inheritance

D. Mitochondrial inheritance

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