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3941 Biochemistry

A 55 year old male patient complains of abnormal growth on right cheek. Patient has a habit of tobacco chewing since 30 years. Radiologic findings reveal 8×8 cm fungating mass, invading maxilla and mandible on right side. Histologic findings are suggestive of squamous cell carcinoma. Which of the following is not true regarding the treatment of this condition?

AThe drugs used are designed to block DNA replication
BMethotrexate and 5-fluorouracil block nucleotide synthesis
CTopoisomerase inhibitors promote the unwinding of parental DNA strands and prevent replication
DThe drugs used for cancer therapy inhibit the enzymes that participate in replication
Biochemistry
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