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1059 Biochemistry

Human serum albumin, the most abundant blood protein, has multiple roles, including acting as a buffer to help maintain blood pH. Albumin can act as a buffer because of which one of the following?

AThe protein contains a large number of amino acids.
BThe protein contains many amino acid residues with different pKa values. (Correct Answer)
CThe amino and carboxyl ends of albumin can donate and accept protons in the range of physiologic pH.
DAlbumin contains peptide bonds that readily hydrolyze, consuming hydrogen and hydroxyl ions.