Mcq Subject: Biochemistry

A 7-year old boy presented with severe abdominal pain. On examination, he had xanthoma. Blood sample was taken for work-up blood sample had milky appearance of plasma. Which of the following lipoprotein is increased?

A. LDL

B. HDL

C. Chylomicron

D. Chylomicron remnants

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A 48-year old lady presented with bony pain and hepatosplenomegaly. On examination of biopsy speci!men from spleen, crumpled tissue paper appearance is seen. Which of the following product is likely to have accumulated?

A. Ganglioside

B. Sulfatide

C. Sphingomyelin

D. Glucocerebroside

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Thiamine is a cofactor for all of the following enzymes except:

A. Alpha ketoglutarate dehydrogenase

B. Branched-chain keto-acid dehydrogenase

C. Succinate dehydrogenase

D. Pyruvate dehydrogenase.

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What high energy phosphate compound is formed in the citric acid cycle through substrate level phosphorylation:

A. ATP

B. TTP

C. ITP

D. GTP

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At physiological pH, which of these amino acids has a positive charge?

A. Valine

B. Aspaic acid

C. Arginine

D. Isoleucine

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CG islands in our DNA are impoant for:

A. Methylation

B. Acetylation

C. t-RNA synthesis

D. DNA replication

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The protein rich in basic amino acids, which functions in the packaging of DNA in chromosomes, is:

A. Histone

B. Collagen

C. Hyaluronic acid binding protein

D. Fibrinogen

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HDL is synthesised in

A. Liver and GIT

B. Liver

C. GIT

D. None of the above

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Which of the following is inclusion of cytoplasm?

A. Endoplasmic reticulum

B. Ribosome

C. Golgi body

D. Glycogen

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An infant presented to the OPD with a history of vomiting and malnutrition. On investigation, the Guthrie test was found to be positive.All are true regarding this disease except?

A. Due to Phenylalanine hydroxylase enzyme defect

B. White patch of hair due to tryptophan deficiency

C. Phenyl acetate positive in urine

D. Mental retardation is present

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