Mcq Subject: Anaesthesia

Which following are postulated mechanism by which propofol acts as antiemetic:-

A. Antidopaminergic activity

B. Depressant effect on the chemoreceptor trigger zone

C. Decreased release of glutamate and aspect able in the olfactory coex and decreased serotonin

D. All of the above

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A 70 kg, 34-yr old athlete is undergoing emergency laparotomy. Due to non-availability of vecuronium bromide, the surgery was conducted under intermittent doses of succinylcholine (total dose: 640 mg) After surgery, there were no respiratory movements and the patient was unable to move his limbs. What was the cause?

A. Pseudocholinesterase deficiency causing prolonged action of succinylcholine

B. Type II depolarizing block caused by succinylcholine

C. Undiagnosed muscle dystrophy complicated by succinylcholine

D. Fasciculations produced by succinylcholine

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CNS affection of a local anesthetic agent leads to?

A. Convulsion

B. Perioral numbness

C. Depression

D. All of the above

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The non depolarizing neuromuscular blocker has a normal activity with all the following except:

A. Myotonia

B. Muscular dystrophy

C. Upper motor neuron lesions

D. Myasthenia gravis

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Ether was first used by

A. Priestley

B. Moon

C. Wells

D. Simpson

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Local Anesthetic first used clinically aEUR’

A. Procaine

B. Lignocaine

C. Bupivacaine

D. Cocaine

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After Hyperventilating for some time holding the breath is dangerous because –

A. Decrease CO2 shift the O2 dissociation curve to the left

B. Alkalosis can lead to tetany

C. It can lead to CO2 Narcosis

D. Due to lack of stimulation by CO2, anoxia can go into dangerous levels

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Which of the following is long acting local anesthetic > 2hrs – a) Bupivacaineb) Prilocainec) Etidocained) Dibucainee) Tetracaine

A. bce

B. acde

C. abcd

D. abde

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True about Boyle’s apparatus – a) Continuous flow machineb) Liquid anesthetic vapours not usedc) Resistance very highd) Resistance low

A. b

B. c

C. ad

D. ab

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A 65-year-old man undergoes a technically difficult abdominal-perineal resection for a rectal cancer during which he receives 3 units of packed red blood cells. Four hours later, in the intensive care unit (ICU), he is bleeding heavily from his perineal wound. Emergency coagulation studies reveal normal prothrombin, paial thromboplastin, and bleeding times. The fibrin degradation products are not elevated, but the serum fibrinogen content is depressed and the platelet count is 70,000/mL. Which of the following is the most likely cause of his bleeding?

A. Delayed blood transfusion reaction

B. Autoimmune fibrinolysis

C. A bleeding blood vessel in the surgical field

D. Factor VIII deficiency

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