Ito cells are found in:
Correct Answer: Liver
Description: Hepatic stellate cells are also known as perisinusoidallipocytes or Ito cells and are much less numerous than hepatocytes. They play a major role in pathological processes. In response to liver damage, they become activated and predominantly myofibroblast-like. They are responsible for the replacement of toxically damaged hepatocytes with collagenous scar tissue - hepatic fibrosis, seen initially in zone 3, around central veins. This can progress to cirrhosis, where the parenchymal architecture and pattern of blood flow are destroyed, with major systemic consequences.
Category:
Anatomy
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