In the histology section given, which marked area is involved in relieving pain in response to massage:
Correct Answer: A
Description: Gate control theory of pain states that innocuous stimuli, such as rubbing a hu area (massage), can block or reduce painful sensations. Such stimulation inhibits C fibres and A delta fibres and activates the large-diameter (Ab) fibersand their activity leads to release of GABA and other inhibitory neurotransmitters by interneurons within the dorsal horn. Transcutaneous electrical nerve stimulation (TENS) of pain relief is also based on gate control theory of pain. Lamina II or substantia gelatinosa acts as the gate where pain modulation occurs. A: Dorsal or posterior horn B: Lateral horn: From T1 to L2, the lateral horn contains the visceral motor efferent cell bodies of the sympathetic system, and From S2 to S4, it contains the visceral motor efferent cell bodies of the parasympathetic system. These cell bodies are collectively referred to as the intermediolateral nucleus. C: Ventral or anterior horn D: Anterolateral tract (spinothalamic tract)
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