Jarisch-Herxhemer reaction is seen in syphilis with:
Correct Answer: Penicillins
Description: Jarisch-Herxheimer reaction Penicillin injected in a syphilitic patient (paicularly secondary syphilis) may produce shivering, fever, myalgia, exacerbation of lesions, even vascular collapse. This is due to sudden release of spirochetal lytic products and lasts for 12-72 hours. It does not recur and does not need interruption of therapy Aspirin and sedation afford relief of symptoms. Essentials of medical pharmacology K D Tripathi Sixth edition Pg no 698
Category:
Pharmacology
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