Job’s syndrome is the following type of immunonodeficiency disease ?
Correct Answer: Disorder of phagocytosis
Description: Ans. is 'd' i.e., Disorder of phagocytosis Classification of primary immunodeficiency syndromes A. Disorders of specific immunity I. Humoral immunodeficiencies (B cell defects) a) X-linked agammaglobulinemia b) Transient hypogammaglobulinemia of infancy c) Common variable immunodeficiency (late onset hypogammaglobulinemia) d) Selective immunoglobulin deficiencies (IgA, IgM or IgG subclasses) e) Immunodeficiencies with hyper-IgM fl Transcobalamin II deficiency II. Cellular immunodeficiencies (T cell defects) a) Thymic hypoplasia (DiGeorge syndrome) b) Chronic mucocutaneous candidiasis c) Purine nucleoside phosphorylase (PNP) deficiency III. Combined immunodeficiencies (B and T cell defects) a) Cellular immunodeficiency with abnormal immunoglobulin synthesis (Nezelof syndrome) b) Ataxia telangiectasia c) Wiskott-Aldrich syndrome d) Immunodeficiency with thymoma e) Immunodeficiency with sho limbed dwarfism 0 Episodic lymphopenia with lymphocytotoxin g) Severe combined immunodeficiencies 'Swiss type' agammaglobulinemia Reticular dysgenesis of de Vaal Adenosine deaminase (ADA) defeciency B. Disorders of complement a) Complement component deficiencies b) Complement inhibitor deficiencies C. Disorders of phagocytosis a) Chronic granulomatous disease b) Myeloperoxidase deficiency c) Chediak-Higashi syndrome d) Leukocyte G6PD deficiency e) Job's syndrome f) Tuftsin deficiency g) Lazy leukocyte syndrome h) Hyper-IgE syndrome i) Actin binding protein deficiency j) Sheachman's disease
Category:
Microbiology
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