You decide not to prescribe sildenafil in a patient because the patient told you that he is taking an antianginal drug. Which of the following can it be?
Correct Answer: Organic nitrates
Description: Nitrates act by increasing cGMP and sildenafil inhibits the breakdown of this compound (by inhibiting phosphodiesterase). Marked increase in cGMP levels may result in the profound hypotension and reflex tachycardia.
Category:
Pharmacology
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