Inward flow of Na+ in heart leads to:
Correct Answer: Action potential
Description: Phase 0 (depolarization), fast sodium channels open. When the cardiac cell is stimulated and depolarizes, the membrane potential becomes more positive. Voltage-gated sodium channels (fast sodium channels) open and permit sodium to rapidly flow into the cell and depolarize it. The membrane potential reaches about +20 millivolts before the sodium channels close.
Key Concept:
Influx of Na+ via fast Na channel leads of phase 0 or beginning of AP in myocardium.
Reference: GUYTON AND HALL TEXTBOOK OF MEDICAL PHYSIOLOGY, THIRTEENTH EDITION(INTERNATIONAL EDITION ) page no111
Category:
Physiology
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