Maximum hypotension is caused by –
Correct Answer: Thioridazine
Description: Cardiovascular System: Thioridazine produces a dose related prolongation of the QTc interval, which is associated with the ability to cause torsade de pointes-type arrhythmias, a potentially fatal polymorphic ventricular tachycardia, and sudden death . Both torsade de pointes-type arrhythmias and sudden death have been repoed in association with thioridazine. A causal relationship between these events and thioridazine therapy has not been established but, given the ability of thioridazine to prolong the QTc interval, such a relationship is possible. Other ECG changes have been repoed it also causes drug induced hypotension Ref Davidson 23rd edition pg 456
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