True about pendred syndrome –
Correct Answer: All
Description: Ans. is 'a' i.e., Diffuse colloid goiter; 'b' i.e., Nodular goiter; 'c' i.e., Mental retardation Pendred syndrome o It is an autosomal recessive disorder o Goiter with sensory neural deafness is seen in pendred syndrome. o Goiter is due to several mutation in TPO gene which lead to defective organification and congenital hypothyroidism. o Hearing loss is usually present at bih but goiter appears after pubey. o Goitre is usually soft and diffuse and later life become nodular. o It is due to defect in a sulfate transpoer protein common to thyroid gland and cochlea.
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now