All the following statements are true for rabies virus except:
Correct Answer: Rabies vaccine is a live attenuated vaccine
Description: Rabies vaccine is a killed vaccine. Option 1 Both active and passive immunization is recommended for grade III exposure to prevent infection. Option 2 The animal reservoir differs from country to country, in India it is dog. Rabies is a zoonotic disease. Other animal reservoirs include silver-haired bats, eastern pipistrelle, raccoons, skunks, foxes, or cats, ferrets, cattle, opossums, fowl, etc. Foxes are more infectious than dogs and other animals. Option 3 Direct fluorescent antibody test of corneal impression smear or hair follicle of nape of neck is the ideal method of antemoem diagnosis of rabies. Option 4 Rabies Vaccine: 1. Neural Vaccines: They are poorly immunogenic and encephalitogenic; hence not used. Semple vaccine: Derived from infected sheep brain BPL: Beta propiolactone derived vaccine (Prepared in Coonoor) Infant mouse brain derived vaccine 2. Non-neural Vaccines: Cell line derived, they are the recommended killed vaccine currently: Purified chick embryo cell (PCEC) Purified Vero cell (PVC) Human diploid cell (HDC).
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Microbiology
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