All are true about scleroderma crisis except?
Correct Answer: Anti - centromere antibody is a positive predictor of disease
Description: Scleroderma crisis occurs in 12% of cases with systemic sclerosis. It is characterised by accelerated hypeension and a rapid decline in kidney function. Histopathological examination shows arcuate aery intimal narrowing and medial proliferation. This is characteristically called onion skinning. Anti-U3-RNP may identify the young patients at risk for scleroderma crisis. Anti-centromere is a negative predictor for scleroderma crisis. Maximum moality in scleroderma occurs due to Pulmonary aery hypeension and pulmonary fibrosis. NOTE : =In Scleroderma renal crisis - Prompt treatment with an ACE inhibitorcan reverse acute renal failure. =ACE inhibitors should be used even if the patient requires dialysis suppo. =MC cause of death in Systemic Sclerosis : Pulmonary Aerial Hypeension
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now