Drug used for Buerger’s disease is
Correct Answer: Xanthinol nicotinate
Description: Thromboangiitis obliterans (Buerger's disease) This is characterised by occlusive disease of small- and medium-sized aeries (plantar, tibial, radial, etc.), thrombophlebitis of the superficial or deep veins and Raynaud's syndrome; it occurs in male smokers, usually under the age of 30 years. Often, only one or two of the three manifestations are present. Histologically, there are inflammatory changes in the walls of aeries and veins, leading to thrombosis. Treatment is total abstinence from smoking, which arrests, but does not reverse, the disease. Established aerial occlusions are treated as for atheromatous disease, but amputations may eventually be required. Ref : Bailey and love 27th edition Pgno : 967 Xanthinol Nicotinate Xanthinol Nicotinate (or xanthinol niacinate or complamina) is a vasodilator It is combination of xanthinol and niacin (nicotinic acid) This vasodilator is used in the treatment of Raynaud's phenomenon or Buerger's disease Ref: Wikipedia
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