‘Weak giants’ are produced by –
Correct Answer: Pituitary adenomas
Description: Ans. is 'd' i.e., Pituitary adenoma o In children and adolescent growth hormone hypersecretion prior to epiphyseal long bone closure causes gigantism. o The muscles often appear enlarged hut they have decreased force generation. o So, hyperpituitarism causes giants which have weak muscles and the most common cause of hyperpituitarism is pituitary adenoma. o Myopathy of hyperpituitarism - o Patients with hyperpituitarism have mild proximal weakness with muscle atrophy. Myopathy is related to the degreed of acromegaly. o Remember that all endocrinal disorders cause myopathy but none of them cause gigantism except hyperpituitarism.
Category:
Pediatrics
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