Hereditary retinoblastomas develop the following chromosomal deletion
Correct Answer: 13q 14
Description: (A) 13q 14# Deletion of a small number of tightly clustered genes result in a number of genetic disorders termed as microdeletion syndromes.> Some of the important ones that have been asked include: Wilm's tumor-Aniridia complex 2 (WAGR syndrome) IIpI36 Part of (deletion of short arm of chromosome 11 Retinoblastoma 13qI4.116 (deletion of part of long arm of chromosome 13) Prader-Willi syndrome, Angelman syndrome6 15qII-136 (deletion of pa rt of long arm of chromosome 15) DiGeorge's syndrome, Velo-cardiofacial syndrome 22qII6 (deletion of part of long arm of chromosome 22)
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Pathology
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