Skin testing with tuberculin-PPD is most widely used in screening for:
Correct Answer: Latent M. tuberculosis infection
Description: Skin testing with tuberculin is used in screening for latent M. tuberculosis infection (LTBI). The test is of limited value in active TB. False-negative reactions are common in immunosuppressed patients and in overwhelming TB. False-positive reactions may be caused by infections with nontuberculous mycobacteria and BCG vaccination. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 1351
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