Which is the most likely inheritance pattern of the disease in the family pedigree cha given below?
Correct Answer: X-Linked dominant type
Description: Circle indicates female, square indicated male. Completely shaded box/circle indicates person having the disease. A daughter always inherits one X chromosome from father & another from mother. A son inherits the Y chromosome from his father and one X chromosome from mother. In the first generation, female is affected by the disease. In the second generation, son is affected by the same disease. In the third generation, all the daughters are affected, not the sons. The given pedigree cha shows that all daughters of affected males have disease, while none of their sons have disease. This is suggestive of X-Linked dominant inheritance.
Category:
Pathology
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