Which of the following medications is contraindicated in patients with allergy to sulphonamides?
Correct Answer: Brinzolamide
Description: Acetazolamide, Dorzolamide and Brinzolamide are sulfonamide derivatives which act by inhibiting carbonic anhydrase (carbonic anhydrase inhibitor). Being sulphonamide derivatives they are contraindicated in patients with allergy to sulphonamides. Ref: Essentials of Pharmacology By K D Tripathi, 5th Edition, Pages 188, 553; Medicinal Chemistry By Sriram, Page 227.
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Pharmacology
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