HIV patient presented with diarrhea. On stool examination, following acid fast organisms was seen. What is the drug of choice in this patient?
Correct Answer: TMP-SMX
Description: MCC of diarrhea in HIV: Cryptosporidium Parvum Diagnosis: Isospora Belli Isosporiasis: Isosporiasis is effectively treated in immunocompetent and immunosuppressed persons with TMP-SMZ (160 mg/800 mg orally two to four times daily for 10 days, with the higher dosage for patients with AIDS). An alternative therapy is pyrimethamine (75 mg orally in four divided doses) with folinic acid (10-25 mg/day orally). Maintenance therapy with low-dose TMP-SMZ (160 mg/800 mg daily or three times per week) or Fansidar (1 tablet weekly) prevents relapse in those with persistent immunosuppression.
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