All of the following statements about carbohydrate antigens are true except
Correct Answer: Good memory response
Description: Ans. (a) Good memory response Ref. Understand the immune system Llge (wary/Black well) "Polysaccharide antigens are ineffective in producing immunogenic memory and this is the reason behind the protein conjugation of polysaccharide vacines." Carbohydrate Polysaccharide antigens: T-cell independent antigens, hence they do not evoke T-cell response which is essential for memory response. Usually present in bacterial cell wall and capsule Stimulates B-cell directly without involving antigen presenting cells, or else produce polyclonal activation of B-cells. Considerably less immunogenic in comparison to peptide antigen Don't exhibit delayed type hypersensitivity In large doses induce tolerance
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Microbiology
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