A fetus born to a mother with history of fever with rash in first trimester of pregnancy shows chorioretinitis, cerebral coical atrophy, cutaneous scarring and bone leg defects. Most probable cause is?
Correct Answer: Maternal varicella
Description: Maternal varicella during the first half of pregnancy may cause congenital malformations by transplacental infection called congenital varicella syndrome Eye defects: Microphthalmia, chorioretinitis, cataracts Neurological: microcephaly, cerebral coical atrophy, neurological dysfunction of bladder and bowel sphincters Cutaneous: scarring in dermatomal origin Bony defects: limb hypoplasia
Category:
Gynaecology & Obstetrics
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