Non-caseating granuloma is characteristically seen in:
Correct Answer: Sarcoidosis
Description: In granulomas associated with ceain infectious organisms (most classically Mycobacterium tuberculosis), a combination of hypoxia and free radical-mediated injury leads to a central zone of necrosis. Grossly, this has a granular, cheesy appearance and is therefore called caseous necrosis. Microscopically, this necrotic material appears as amorphous, structureless, eosinophilic, granular debris, with complete loss of cellular details. The granulomas in Crohn disease, sarcoidosis, and foreign body reactions tend to not have necrotic centers and are said to be non-caseating.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now